WebTizanidine, an alpha-2 adrenergic agonist, is a centrally active muscle relaxant and a spasmolytic drug. The aim of our study was to investigate the activity of tizanidine on …

Using antidepressants for depression in people with epilepsy

WebGreatest risk of ↓ seizure threshold: at start of therapy; high doses; abrupt ↑ of dose or use of more than one antipsychotic. Incidence likely <1% Haloperidol Since haloperidol may ↓ the seizure threshold, the drug should be used with caution in patients receiving anticonvulsant agents and in those with a history of seizures or EEG WebMar 1, 2013 · Evidence supporting the notion that neuroleptic drugs lower the seizure threshold is based on studies that are not sufficiently controlled and typically report patients with other risk factors for seizures. Case reports, often complicated by polypharmacy and other risk factors for seizures, form a substantial portion of the available literature. tingchen fu

Antibiotic-induced epileptic seizures: mechanisms of action and ...

WebCiprofloxacin, like other fluoroquinolones, is known to trigger seizures or lower the seizure threshold. Cases of status epilepticus have been reported. As with all fluoroquinolones, use ciprofloxacin with caution in epileptic patients and patients with known or suspected CNS disorders that may predispose to seizures or lower the seizure ... WebYes. Most seizure medicines (also known as antiepileptic drugs or AEDs) interact with each other and with other medicines. Such interactions are common and can be dangerous. The effects of interactions between two medications vary. Some seizure medicines can lower or raise the levels of other types of medicines in your blood. Web1. Seizure threshold can be measured by the time necessary for a seizure to occur, as the amount of convulsant drug necessary to induce a seizure, or as the number of stimulations required to induce seizure. Lowering the seizure threshold corresponds to a proconvulsant effect, whereas increasing the seizure threshold means an anticonvulsant effect. parvathi preethan