WebJun 1, 2024 · Daphnane-type diterpenoids Molecular networking Cytotoxic activity 1. Introduction Daphne genkwa Sieb. et Zucc (Thymelaeaceae) has been studied for many years as a classical medicine in traditional Chinese medicine. Its main chemical components include flavonoids, lignans, and diterpenoids (Giorgi et al., 2024; Zhao et al., 2024).
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WebJun 15, 2010 · Daphnane‐Type Diterpenoids from the Flower Buds of Daphne genkwa Ling‐Zhi Li School of Traditional Chinese Materia Medica, Key Laboratory of … WebJul 15, 2024 · The genus Daphne comprises 70 shrub species distributed in Europe, temperate and subtropical Asia (Brickell and Mathew, 1976), and North Africa (Marks, 1997; Halda, 1999). D. gnidium grows around the Mediterranean basin, in Southern Europe, Northern Africa and the Middle East (Cottiglia et al., 2001).
WebThe daphnane-type diterpene gnidimacrin, isolated from the root ofthe Chinese plant, Stellera chamoejasme L. was found to strongly inhibit cell growth of human leukemias, stomach cancers and non-small cell lung cancers in vitro at concentra- tions of to I O-Io M. WebFeb 13, 2014 · A new coumarin, edgeworic acid (1), was isolated from the flower buds of Edgeworthia chrysantha, together with the five known coumarins umbelliferone (2), 5,7-dimethoxycoumarin (3), daphnoretin (4), edgeworoside C (5), and edgeworoside A (6). Their structures were established on the basis of spectral data, particularly by the use of 1D …
WebNov 1, 2014 · (2009) Trigochilides A and B, two highly modified daphnane-type diterpenoids from Trigonostemon chinensis. Organic Letters, 11, 4080–4083; (d) Zhang L, Luo RH, Wang F, Jiang MY, Dong ZJ, Yang LM, Zheng YT, Liu JK. (2010) Highly functionalized daphnane diterpenoids from Trigonostemon thyrsoideum. Organic … WebDaphnane orthoesters are the active ingredients of plant remedies from the Western, Chinese and African traditional medicine, and have provided important tools to …
WebMay 14, 2014 · Phytochemical investigation of whole plants of Euphorbia pilosa led to the isolation and identification of two new daphnane‐diterpenoid glucosides, euphopilosides A and B (1 and 2, resp.), and a new ent‐abietane, euphopilolide (3), together with eight known compounds.Compounds 1 and 2 are the first daphnane‐type diterpenoid glycosides. …
WebBackground: Tyrosine kinase inhibitors (TKIs), such as gefitinib, are widely used as standard treatments for non-small cell lung cancer (NSCLC) patients with e great waldingfield newsWebMay 9, 2014 · A new daphnane-type diterpenoid, named daphnegiraldigin ( 1 ), was isolated from the ethanol extract of the stem barks of Daphne giraldii Nitsche. Its structure was defined on the basis of spectral analysis. Daphne giraldii Nitsche (Thymelaeaceae) is widely distributed in the northwest areas of China, such as Shanxi, Gansu, and Qinghai … florida department of corrections indeedWebTrigocherrin A, the first natural chlorinated daphnane diterpene orthoester from Trigonostemon cherrieri. P. Allard, P. Leyssen, M. Litaudon, 2012, Organic letters. Sharing and community curation of mass spectrometry data with Global Natural Products Social Molecular Networking ... florida department of corrections itnWebMay 27, 2011 · Nine new daphnane-type diterpenoids (1-9), named trigohownins A-I, and four known analogues were isolated from Trigonostemon howii. Their structures were elucidated on the basis of extensive NMR and MS analyses. florida department of corrections milton flWebTo discover diterpenoids that naturally possess chemical weapons against cancer, the biological and chemical diversity of the flower buds of Daphne genkwa Sieb. et Zucc was investigated. Guided by LC-MS/MS analysis … great waldingfield post officeWebOct 31, 2024 · Most of the natural diterpenoids occurring in the genus Daphne belong to the daphnane type featuring a 5/7/6-tricyclic ring system with polyhydroxyl groups at C-3, C-4, C-5, C-9, C-13, C-14, or C-20 and an orthoester function located at ring C, which could be further categorized into four major classes: great waldingfield parishWebDaphne definition, a nymph who, when pursued by Apollo, was saved by being changed into a laurel tree. See more. florida department of corrections job fair